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ABOUT US
The University of Pennsylvania School of Medicine is ranked #2 in the nation for receipt of NIH research funds; and ranked #3 in the nation in U.S. News & World Report’s most recent ranking of top research-oriented medical schools. Supporting 1,400 fulltime faculty and 700 students, the School of Medicine is recognized worldwide for its superior education and training of the next generation of physician-scientists and leaders of academic medicine.

The University of Pennsylvania Health System, the School of Medicine, the Abramson Cancer Center, and the Department of Obstetrics and Gynecology have made ovarian cancer a top research and clinical priority at PENN and have jointly invested significant resources to create the new Ovarian Cancer Research Center launched in July 2007 under the leadership of George Coukos, MD, PhD.

JOB DESCRIPTION
Well-established research groups in the Ovarian Cancer Research Center have Post-doctoral Research Fellow positions available focused on modeling the human ovarian tumor microenvironment using state-of-the-art mouse xenograft models. The overall goal of the project is to study the microenvironment editing by tumor cells and the mechanisms implicated in the induction of immune tolerance, tumor-promoting inflammation, and angiogenesis in human ovarian cancer.

QUALIFICATIONS
PhD or MD/PhD in the fields of immunology, tumor biology, molecular and cell biology, genetics, or biochemistry is required. Experience in the following areas is beneficial:

• Cellular immunology and functional assays
• Cloning and manipulation of cDNA, vector construction and modification
• Flow cytometry, immunofluorescence, confocal microscopy, image processing
• Xenografting in immune-deficient mice, in vivo imaging (fluorescence, bioluminescence)
• Mammalian cell culture, transient and stable transfection, cell separation, SDS-PAGE,
• Immunoprecipitation, ELISA and Western blotting

To be successful in this position, the Post-Doctoral Fellow must be able to organize work and think independently, able to develop creative approaches to experimental design, and able to work well collaboratively in an intense work environment.

JOB TYPE
Full-time position
COMPENSATION
Salary based on NIH scale + excellent benefits
OPENING DATE
Immediately
HOW TO APPLY
To apply for this position, please submit electronically a formal cover letter, CV, and contact information for three professional references to:

Gwenn Danet-Desnoyers, Ph.D.
gdanet@upenn.edu

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